Gall Bladder Cancer

The most common symptoms caused by gallbladder cancer are jaundice, pain, and fever. In patients whose superficial cancer is discovered on pathological examination of tissue after gallbladder removal for other reasons, the disease is often cured without further therapy. In patients who present with symptoms, the tumor is rarely diagnosed preoperatively. Cholelithiasis is an associated finding in the majority of cases. For localized cancer, the standard surgical procedure is removal of the gallbladder, a wedge resection of the liver, resection of the extrahepatic bile duct, and resection of the regional (N1 and N2) lymph nodes. For unresectable cancer, significant symptomatic benefit can often be achieved with relief of biliary obstruction. Palliative treatment options may include percutaneous transhepatic radiologic catheter bypass or endoscopically placed stents, external-beam radiation therapy and palliative surgery to relieve bile duct obstruction.

 

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