Melanoma occurs when melanocytes turn malignant. When melanoma starts in the skin, the disease is called cutaneous melanoma. Melanoma may also occur in the eye. Rarely, melanoma may arise in the meninges, the digestive tract, lymph nodes or other areas where melanocytes are found. Often, the first sign of melanoma is a change in the size, shape, color or feel of an existing mole. Diagnosis is usually by excision biopsy. Treatment depends on the stage of the tumour.


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