Metabolic Syndrome
Metabolic syndrome is characterized by a group of metabolic risk factors in one person. They include: abdominal obesity, atherogenic dyslipidaemia (high triglycerides, low HDL cholesterol and high LDL cholesterol), elevated blood pressure, insulin resistance or glucose intolerance, prothrombotic state (e.g. high fibrinogen or plasminogen activator inhibitor-1 in the blood) and proinflammatory state (e.g., elevated C-reactive protein in the blood). The primary goal of clinical management of the metabolic syndrome is to reduce the risk for cardiovascular disease and type II diabetes. Then, the first-line therapy aims to reduce the major risk factors for cardiovascular disease: smoking cessation; and reduction of LDL cholesterol, blood pressure and glucose levels to the recommended levels.
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