General Medicine

Venous Thromboembolic (VTE) Disease, Deep Vein Thrombosis (DVT)

Early recognition and appropriate treatment of deep venous thrombosis (DVT) and pulmonary thromboembolism (PTE) is most important. Identify known risk factors for venous thrombosis. The single most powerful risk marker for DVT is a prior history of VTE. Many patients are asymptomatic. The primary objectives of the treatment of DVT are to prevent pulmonary embolism, reduce morbidity, and prevent or minimize the risk of developing the postphlebitic syndrome. Anticoagulation remains the mainstay of initial treatment for DVT.Regular unfractionated heparin was the standard of care until the recent introduction of low-molecular-weight-heparin. The optimal regimen for the treatment of DVT is anticoagulation with heparin followed by full anticoagulation with oral warfarin for 3-6 months. Surgical therapy for DVT may be indicated when anticoagulant therapy is ineffective, unsafe, or contraindicated.

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