General Medicine

Fever: Septicaemia

Septicemia is sepsis of the bloodstream caused by bacteremia, which is the presence of bacteria in the bloodstream. It is caused by a systemic inflammatory response leading to widespread activation of inflammation and coagulation pathways. It may progress to dysfunction of the circulatory system and, even under optimal treatment, may result in the multiple organ dysfunction syndrome and eventually death. It is more common and as well as more dangerous in infants, elderly, immunocompromised and critically ill patients. The therapy rests primarily on administering the right antibiotics, surgical drainage of infected fluid, if any, fluid replacement and appropriate support for organ dysfunction. Delay in identifying severity and administering the right treatment after sepsis has been recognized as the main reason for high mortality.

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