General Medicine

Tired patient

A patient presenting with unexplained tiredness that has lasted beyond levels of comfort needs serious consideration. Both the diagnostic evaluation as well as the management should be done in an orderly manner. If a medical illness is the cause it is usually evident on initial presentation. A thorough history and complete physical examination with some screening laboratory tests, can rule out most medical causes of fatigue. Depression or generalized anxiety disorder, account for a significant proportion of cases of chronic fatigue. More significant are cases wherein a patient who is otherwise "always well" presents with extreme tiredness.

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