Haemat Onco » Miscellaneous

Blood Transfusion Guidelines

Transfusion decisions should be based on clinical assessment of the patients and laboratory test results. There are no absolute indications and few contraindications to blood transfusion. These guidelines are intended as an aid in decision making. Some of the indications for RBC transfusion include symptomatic anemia in euvolemic patient Preoperative hemoglobin less than 9gm/dl with expected blood loss of more than 500 mL. and hemoglobin less than 7 gm/dL in a critically ill patient. Platelets are indicated for the prevention or control of bleeding due to thrombocytopenia or platelet dysfunction. Platelets may be provided as pooled whole-blood derived platelet concentrates ("random donor" platelets) or as apheresis platelet concentrates. Plasma is provided as Fresh Frozen plasma (FFP). FFP is plasma within 24 hours of thawing. Cryoprecipitated antihemophilic factor ("cryo") is a concentrate of Factor VIII, von Willebrand's factor, fibrinogen, and Factor XIII. Each unit contains a minimum of 80 U of Factor VIII and typically 250 mg of fibrinogen.

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