Lab medicine » Hematology

ESR and it's significance in Health and Disease

The Erythrocyte Sedimentation Rate (ESR) is a simple method for evaluating this acute phase plasma protein response. ESR helps to differentiate inflammatory Vs non-inflammatory joint disease (Rheumatoid arthritis versus Osteoarthritis). Marked elevations of ESR (>100mm/hr are associated with severe deep tissue infections as tuberculosis or osteomyelitis, systemic lupus erythematosus (SLE), polymyalgia Rheumatica, metastatic carcinoma, myeloma etc. Increase in ESR is seen in monoclonal gammopathy, increasing age and increasing dietary lipid intake. ESR maybe also spuriously elevated in patients on heparin.

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