Rheumatoid Factors / Rheumatoid Antibody
Rheumatoid Factors/ Rheumatoid Antibody are autoantibodies that are directed against epitopes on the Fc portion of Immunoglobulin molecules- they occur within the IgM, IgG and IgA classes. Classical RF is the 19S IgM molecule. Rheumatoid factors are non-specific and may occur in a broad range of diseases and are found in TB, Leprosy, and Chronic active hepatitis, infective endocarditis, pulmonary fibrosis and essential mixed cryoglobulinaemia.
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