Metabolic Disorders

Lipids and Dyslipidaemias

Dyslipidaemias are disorders of lipoprotein metabolism, including lipoprotein overproduction or deficiency. There are four types of disorder which manifest as elevation of the serum total cholesterol, elevation of low-density lipoprotein (LDL) cholesterol, elevation of triglyceride concentrations and a decrease in the high-density lipoprotein (HDL) cholesterol concentration. Diet control and exercise are important steps in the management of dyslipidaemia. Statins decrease LDL cholesterol; fibrates decrease serum triglycerides, nicotinic acid increases HDL cholesterol and decreases LDL cholesterol.

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