Non Hodgkin's Lymphoma
NHL includes many clinicopathologic subtypes, each with distinct epidemiologies; aetiologies; morphologic, immunophenotypic, genetic, and clinical features; and responses to therapy. NHL may develop in any organ associated with the lymphatic system (e.g. spleen, lymph nodes, or tonsils). Most cases start with infiltration of lymph nodes, but some subtypes may be restricted to other lymphatic organs. The diagnosis of NHL is by biopsy of involved tissue. The numerous subtypes of non-Hodgkin's lymphoma are typically grouped by their histologic grade, or aggressiveness. The treatment of indolent or low-grade lymphoma may initially be supportive, while aggressive or high-grade non-Hodgkin's lymphoma is typically treated with chemotherapy or radiation therapy.
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