Neurology » Infections

Guillain-Barré Syndrome

Guillain-Barré syndrome is a heterogeneous grouping of immune-mediated processes generally characterised by motor, sensory, and autonomic dysfunction. In its classic form, GBS is an acute inflammatory demyelinating polyneuropathy characterized by progressive symmetric ascending muscle weakness, paralysis, and hyporeflexia with or without sensory or autonomic symptoms. However, variants involving the cranial nerves or pure motor involvement are not uncommon. In severe cases, muscle weakness may lead to respiratory failure, and labile autonomic dysfunction may complicate the use of vasoactive and sedative drugs. GBS has been associated with antecedent bacterial and viral infections, administration of certain vaccinations, and other systemic illnesses. Only plasma exchange therapy and IV immune serum globulin have proven effective. Both therapies have been shown to shorten recovery time by as much as 50%.

In order to proceed further, you need to have an account on IDG.
Create a new account now

Registered users, you can login below to access this page.