Diabetic Cardiomyopathy

The concept of diabetic cardiomyopathy is based upon the idea that diabetes is the factor which leads to changes at the cellular level, leading to structural abnormalities. This is a specific cardiomyopathy related to diabetes seen in patients in whom there is no other cause i.e. no presence of hypertension,valvular heart disease congenital heart disease or alcoholic heart disease to account for congestive heart failure. Up to half of patients have heart failure due to diastolic dysfunction despite normal LV ejection fraction.

Early abnormalities are defined by an ejection fraction with reduced early diastolic prolongation of isovolumetric relaxation filling, the presence of which confirms dysfunction.

 

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