Endocrine » Thyroid & Parathyroid

Subacute Thyroiditis

Sub-acute thyroiditis is a condition that is characterized by painful inflammatory destruction of the thyroid resulting in low-uptake thyrotoxicosis associated with an elevation of inflammatory markers, followed by a slow restoration of euthyroidism. The term sub-acute thyroiditis (SAT) conventionally has been used interchangeably with sub-acute granulomatous (de Quervain) thyroiditis, which was the first syndrome described as causing inflammation and release of pre-formed hormone from the gland. During the initial phase of the illness, serum thyroxine (T4) and free T4 concentrations are elevated in almost all patients. Many authorities believe that corticosteroids are the mainstay of the.

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