Hepatitis C
If acute viral hepatitis is suspected, the following tests should be performed: IgM antibodies against hepatitis A, HBsAg, IgM antibodies against hepatitis B core antigen and hepatitis C antibodies. Other viral markers for viral hepatitis D, infectious mono nucleosis, cytomegalovirus infection, herpes simplex virus and parvovirus B19 may be asked in a few selected cases. A specific diagnosis of Hepatitis C is obtained by determining serum hepatitis C antibodies and RNA (HCV RNA). Liver biopsy is indicated in a patient with positive HCV-PCR-test and normal ALT, and with genotypes 1 and 4 before considering therapy; signs of chronic hepatitis in the biopsy are an indication for treatment.
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