Mixed connective tissue disease

Connective tissue diseases are disorders featuring abnormalities involving the collagen and elastin; those due to genetic inheritance are Marfan syndrome and Ehlers-Danlos syndrome. The classic immune-related connective tissue diseases include systemic lupus erythematosus, rheumatoid arthritis, scleroderma, polymyositis and dermatomyositis. Mixed connective tissue disease (MCTD) is a rare autoimmune disorder that causes signs and symptoms of three connective tissue diseases viz. lupus, scleroderma and polymyositis. They occur most often in women. Treatment is essentially NSAIDs and steroids.


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