Rheumatology » Articular Rheumatism

Polymyositis

Polymyositis is an idiopathic inflammatory myopathy, immune-mediated muscle inflammation and vascular damage occurs. Patients present with symmetric proximal muscle weakness with insidious onset. There is muscle tenderness on palpation. CKP level is raised; it usually is 5-50 times above the reference level. Steroids are started at a high dose and tapered after 1-3 months, depending on the clinical response. If this is not successful, other immunosuppressive agents azathioprine and methotrexate are used.

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