Pseudogout refers to the clinically evident acute synovitis with red, swollen and tender joints that resemble gouty arthritis. Pseudogout is a rheumatologic disorder with varied clinical manifestations due to precipitation of calcium pyrophosphate dihydrate crystals in the connective tissues. CPPD crystal deposition disease is a polyarticular arthritis, although it can initially present as monoarticular. Both can be differentiated on the basis of the analysis of synovial fluid and radiological findings Since crystal deposition can not be reversed, treatment is aimed preventing further crystal formation and reducing symptoms. If CPPD results from underlying metabolic abnormalities (hyperparathyroidism, hemochromatosis, hypophosphatasia, or hypomagnesemia) these have to be treated directly.


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